Figure 6.
Experimental results for magnetic guidance on accumulation of magnetic double emulsion nanocapsules (MDCs) and lactoferrin (Lf)-tethered MDCs (LF-MDCs) in brain tumour of mice and therapy on tumour volume. (a) Variation in fluorescence intensity of nude mice bearing two intravenously injected tumours after 1 and 5 d, with no magnetic treatment on the left tumour. (b) Effect of the treatment on tumour size. (c) Fluorescence microscopic images on cellular uptake of RG2 cells incubated with MDCs, Lf-MDCs and Lf-MDCs under a magnetic field. (d) Comparison of cellular uptake efficiency for difference cases in (c). (Reproduced with permission from Fang et al. [10] (Copyright 2014 Wiley Online Library)). (Online version in colour.)