Table 2.
Risk factor analysis for being CT positivea.
Univariate analysis |
Multivariate analysisc |
|||||||
---|---|---|---|---|---|---|---|---|
Characteristic | No. of participants | No. (%) with CTb | OR | 95%CI | P-value | OR | 95%CI | P-value |
Age | 709 | 51 (7.2) | 0.94 | 0.89–0.99 | 0.01 | 0.95 | 0.90–1.00 | 0.06 |
Clinic | ||||||||
1 | 387 | 34 (8.8) | 1 | 1 | ||||
2 | 92 | 3 (3.3) | 0.35 | 0.11–1.17 | 0.09 | 0.36 | 0.10–1.29 | 0.12 |
3 | 72 | 2 (2.8) | 0.30 | 0.07–1.26 | 0.10 | 0.31 | 0.07–1.43 | 0.13 |
4 | 158 | 12 (7.6) | 0.85 | 0.43–1.69 | 0.65 | 0.47 | 0.20–1.07 | 0.07 |
Contact of a CT positive | ||||||||
No | 617 | 26 (4.2) | 1 | 1 | ||||
Yes | 48 | 21 (43.8) | 17.68 | 8.85–35.33 | < 0.001 | 17.33 | 8.28–36.27 | < 0.001 |
Not known | 44 | 4 (9.1) | 2.27 | 0.76–6.83 | 0.14 | 2.94 | 0.91–9.45 | 0.07 |
Taken CT-active medication in last 6 weeks | ||||||||
No | 669 | 47 (7.0) | 1 | |||||
Yes | 40 | 4 (10.0) | 1.47 | 0.50–4.31 | 0.48 | |||
Symptomatic | ||||||||
No | 591 | 38 (6.4) | 1 | |||||
Yes | 118 | 13 (11.0) | 1.8 | 0.93–3.50 | 0.08 | |||
STI last year | ||||||||
No | 641 | 41 (6.4) | 1 | 1 | ||||
Yes | 68 | 10 (14.7) | 2.52 | 1.20–5.30 | 0.01 | 2.09 | 0.87–4.99 | 0.10 |
Currently menstruating | ||||||||
No | 634 | 46 (7.3) | 1 | |||||
Yes | 71 | 4 (5.6) | 0.76 | 0.27–2.19 | 0.62 | |||
Has sex withd | ||||||||
Men | 665 | 47 (7.1) | 1 | |||||
Women | 20 | 1 (5.0) | 0.70 | 0.09–5.28 | 0.72 | |||
Both | 23 | 3 (13.0) | 1.98 | 0.57–6.88 | 0.29 |
CT, Chlamydia trachomatis; OR, Odds ratio; 95% CI, 95% Confidence Interval; STI, Sexually transmitted infection.
For each characteristic the number of participants and the proportion of these with a CT infection are shown.
CT positive defined as reference standard: either positive initial comparator test result (when in agreement with io® CT assay result); or positive by at least two of three of the initial comparator test, io® CT assay and, Artus CT assay).
Adjusted for age, clinic, contact status and STI in the last year (age and clinic considered a priori risk factors and included in all models).
Sexual orientation unknown for one participant.