Fig. 2.

Individual plot of quality assessment for reviewed studies. Each study was initially assessed against 12 previously used criterial [39]. In the current study two additional criteria (criteria 13 and 14, as per Table 1) were included in order to assess the impact of acute neuropathy on treatment compliance in the first 14 days. The cumulative scores for successive criterion in each study are joined by a connecting line; based on the final cumulative score (criterion 14) studies were deemed to be of low (< 7), medium (7–9) and high quality (≥10). The addition two criteria revealed that only 2 of the 14 (highlighted in red) studies documented the impact of acute neuropathy in the first 14 days on treatment