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Magnitude, R2*, and QSM images from MRI gradient-echo imaging of rat brains before and after (A) 4 wk of daily injections and (B) 4 wk of daily injections and 1 wk without injections. Each image was postprocessed from all echoes of the gradient-echo acquisition as described in the Methods section. Contrast enhancement with repeated dosing of ferumoxytol and Molday ION was primarily localized to the ventricles.
