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. 2018 Jan 9;28:62–69. doi: 10.1016/j.ebiom.2018.01.001

Table 5.

Degree of diagnostic accuracy in CRCs and Non-CRCs.

CRC n = 103 Non-CRC n = 89 Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%) Youden index
All three positive 92 2 97.8 89.3 97.8 88.7 92.5 0.871
At least two positive 103 10 100 88.8 91.2 100 94.8 0.888
At least one positive 103 19 100 78.6 84.4 100 90.1 0.786
SATB2 +/CK20 + 92 1 89.3 97.8 97.9 88.8 93.2 0.871
SATB2 +/CDX2 + 95 1 92.2 97.8 97.9 91.6 94.8 0.900
CK20 +/CDX2 + 103 9 97.1 88.7 90.9 96.3 93.2 0.858
SATB2 + 95 1 92.2 96.7 96.9 91.5 94.3 0.889
CK20 + 100 13 97.1 83.1 86.9 96.1 90.6 0.802
CDX2 + 103 12 100.0 85.4 60.4 88.8 93.2 0.854

CRC, colorectal cancer.