Table 1.
The clinical characteristics of the study subjects
| TED group (31 eyes of 17 patients) |
Non-TED group (31 eyes of 17 controls) |
P value† | |
|---|---|---|---|
| Age (yr) | 44.7 ± 11.0 | 44.7 ± 11.2 | 0.785 |
| CAS | 1.6 ± 0.7 | – | – |
| Disease duration (months) | 47.3 ± 63.5 | – | – |
| Exophthalmos (mm) | 20.4 ± 4.3 | 16.5 ± 1.1 | < 0.001* |
| Lagophthalmos (mm) | 0.9 ± 1.9 | 0.0 ± 0.0 | 0.015* |
| Partial blinking rate (%) | 58.4 ± 34.7 | 55.1 ± 34.1 | 0.702 |
| ST-1 (mm) | 12.6 ± 9.0 | 13.0 ± 10.2 | 0.885 |
| SPEED (score) | 7.4 ± 4.1 | 6.8 ± 4.7 | 0.509 |
| MG dysfunction signs‡ (eyes) | 27 | 1 | < 0.001* |
| MGd (score) | 2.1 ± 0.9 | 2.2 ± 0.9 | 0.555 |
| MGE (score) | 0.6 ± 1.1 | 0.8 ± 0.9 | 0.379 |
| MGYLS (score) | 4.7 ± 3.1 | 3.0 ± 2.5 | 0.014* |
| TMQS (score) | 10.1 ± 8.0 | 8.5 ± 4.9 | 0.412 |
| LLT (nm) | 74.1 ± 21.7 | 72.0 ± 21.9 | 0.654 |
†Fisher’s exact test was used to test the between-group differences in MG dysfunction signs, while the Wilcoxon signed-rank test was used to test other parameters
(*) Statistically significant (P < 0.05)
‡MG dysfunction signs, signs of meibomian gland (MG) dysfunction, including irregular lid margin, vascular engorgement, plugged meibomian gland orifices, and displacement of mucocutaneous junction
CAS Clinical activity score, ST-1 Schirmer test 1, SPEED Scores of SPEED questionnaire, MGd MG dropout, MGE MG expressibility, MGYLS MG yielding liquid secretion, TMQS Total meibum quality score, LLT Lipid layer thickness