Table 2.
Comparison between active and inactive thyroid eye diseases
| Active TED† (11 eyes of 6 patients) |
Inactive TED‡ (20 eyes of 11 patients) |
P value§ | |
|---|---|---|---|
| Age (yr) | 45.2 ± 16.1 | 44.4 ± 7.3 | 0.679 |
| Sex (female: male) | 7: 4 | 11: 9 | 0.718 |
| Disease duration (months) | 80.8 ± 96.8 | 28.9 ± 20.5 | 0.264 |
| Exophthalmos (mm) | 23.1 ± 4.3 | 18.5 ± 3.3 | 0.005* |
| Lagophthalmos (mm) | 2.13 ± 2.67 | 0.18 ± 0.59 | < 0.001* |
| Partial blinking rate (%) | 58.2 ± 29.9 | 58.5 ± 37.8 | 0.834 |
| ST-1 (mm) | 9.2 ± 5.6 | 14.5 ± 10.0 | 0.199 |
| SPEED (score) | 7.1 ± 4.6 | 7.6 ± 3.9 | 0.803 |
| MG dysfunction signs# (no. of eyes; %) | 11 (100%) | 16 (80%) | 0.269 |
| MGd (score) | 2.5 ± 0.9 | 1.8 ± 0.7 | 0.03* |
| MGE (score) | 0.2 ± 0.4 | 0.9 ± 1.2 | 0.148 |
| MGYLS (score) | 5.4 ± 2.9 | 4.3 ± 3.1 | 0.362 |
| TMQS (score) | 8.2 ± 5.5 | 11.2 ± 9.0 | 0.482 |
| LLT (nm) | 86.3 ± 18.0 | 67.4 ± 21.0 | 0.024* |
†,‡Patients with thyroid eye diseases (TED) were classified by the clinical activity score (CAS) as having active TED (CAS 2−3) or inactive TED (CAS 0−1); §Fisher’s exact test was used to test the between-group differences in sex and MG dysfunction signs, while Wilcoxon’s rank-sum test was used to test other parameters. (*)Statistically significant (P < 0.05)
#MG dysfunction signs, signs of meibomian gland (MG) dysfunction, including irregular lid margin, vascular engorgement, plugged meibomian gland orifices, and displacement of mucocutaneous junction