Fig. 1.

Comparative genomic analysis of the YidC family in crenarchaea. A. Gene neighborhoods of predicted yidC genes in archaea. For each arCOG gene neighborhoods for representative organisms are shown. Genes are shown by block arrows with the length roughly proportional to the size of the corresponding gene. Homologous genes are indicated by the same color. The annotated arCOGs are indicated above the respective arrows. The arCOG05556 gene is represented by a white arrow to show that the evidence for it being the YidC subunit is weak. Abbreviations: RP S5 – ribosomal protein S5, RP L30 – ribosomal protein L30, RP L15 – ribosomal protein L15, SecY – preprotein translocase subunit SecY, RP L34 – ribosomal protein L34E, AdkA – archaeal adenylate kinase, PolB – DNA polymerase elongation subunit (family B). B. Phyletic pattern of predicted YidC subfamilies in different archaeal lineages. Phyletic patterns for the indicated arCOG families (filled circles show presence and empty circles show absence of the respective COG members) are superimposed over the phylogenetic tree of crenarchaea. The tree topology is based on the phylogeny of concatenated ribosomal proteins [81].