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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Clin Cancer Res. 2017 Sep 12;23(23):7324–7332. doi: 10.1158/1078-0432.CCR-17-1561

Figure 2. TMEM16A correlates with in vivo Erk 1/2 activation and suppression of Bim.

Figure 2

A & B: UM-SCC1 TMEM16A overexpressing (TMEM16A) tumor xenografts were significantly larger than control tumor xenografts. C: UM-SCC-1 TMEM16A tumors demonstrated significantly less TUNEL staining than control tumors. D: UM-SCC1 TMEM16A overexpressing tumors expressed significantly greater pErk 1/2 with selective suppression of Bim. All data expressed as mean ± SEM relative to control conditions; *p < .05. Blots cropped for conciseness; full length blots available in supplemental materials.