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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Cancer Prev Res (Phila). 2017 Sep;10(9):494–506. doi: 10.1158/1940-6207.CAPR-16-0322

Figure 1.

Figure 1

Adipocyte-secreted cytokines (e.g., leptin, adiponectin, MCP-1, TNFα, IL-6, IL-8) and adipocyte-induced conditions (e.g. hypoxia) and their impact on the main hallmarks of cancer development: proliferation, angiogenesis, metastasis.