Schematic summarizing essential tremor (ET) genes identified to date. The penetrance (y-axis) and variant frequency (x-axis; rare, uncommon, and common variants) are indicated. FUS/TLS, fused in sarcoma/translated in liposarcoma; GWAS, genomewide association studies. (Adapted from Verstraeten A, Theuns J, Van Broeckhoven C (2015) Progress in unraveling the genetic etiology of Parkinson disease in a genomic era. Trends Genet 31: 140–149.)