Table 1. Effects of treatments on IPA® Diseases & Functions related to cell death and survival.
| IPA Diseases & Functions | PFOA | BPA | z-score 1 DEHP | ATR | TBT |
|---|---|---|---|---|---|
| Necrosis | 1.885 | -1.109 | |||
| necrosis of liver | 1.067 | ||||
| necrosis epithelial cells | 1.054 | ||||
| necrosis prostate cancer cells | -1.555 | ||||
| Apoptosis | 1.434 | 1.037 | -1.723 | ||
| apoptosis tumor cells | 1.386 | ||||
| apoptosis leukocytes | -0.851 | ||||
| apoptosis breast cancer | 1.925 | ||||
| apoptosis prostate cancer cells | -1.660 | ||||
| cell death of immune cells | -1.237 | -2.139 | -2.449 | ||
| cell death of lymphocytes | -1.640 | -1.924 | |||
| cell death of macrophages | -1.853 | ||||
| cell death of epithelial cells | 1.150 | ||||
| cell death of osteosarcoma cells | -3.162 | ||||
| cell death of cancer cells | -3.049 | ||||
| cell death tumor cells | -3.049 | ||||
| cell death connective tissue | -1.201 | ||||
| cell death fibroblasts | 1.066 | ||||
| cell death of blood cells | -2.238 | -2.236 | |||
| cell death | -0.992 | ||||
| cell death cervical cancer | -0.847 | ||||
| cell survival | -2.981 | ||||
| cell viability cancer/carcinoma | -1.964 | 2.066 | |||
| cell viability | 2.952 | ||||
| cell proliferation | 2.025 |
1
Z-scores indicating significant increase (z > 1.96) or decrease (z < - 1.96) of disease/functions are shown in bold.