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. 2018 Apr 13;13(4):e0195516. doi: 10.1371/journal.pone.0195516

Fig 4. Mucosal IL-1R1 signaling is involved in POI.

Fig 4

(A-C) WT mice underwent IM. Gene expression of (A) IL-1R1; (B) IL-1α and (C) IL-1β was analyzed in mucosal tissue of jejunal and ileal bowel segments after indicated time. (D) Basal gene expression of antimicrobial proteins was quantified in IL-1R1 deficient compared to control mice of jejunal and ileal mucosa. n = 5 for all groups. Statistical analysis was done by 1-way ANOVA, followed by Bonferroni post hoc test or t-test, respectively. *p < 0.05, **p < 0.01, ***p < 0.001 vs. indicated groups.