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. 2018 Apr 13;13(4):e0195564. doi: 10.1371/journal.pone.0195564

Table 2. Self-care behavior stratified by four patient groups based on the presence and/or absence of knowledge about the self-limited disease course and subjective discomfort during the last common cold (n = 2,204).

Group 1 ☺ Group 2 Group 3 Group 4 ☹ p-value
(+) knowledge (-) discomfort (-) knowledge (-) discomfort (+) knowledge (+) discomfort (-) knowledge (+) discomfort
Group size, n, % 510 23.1 138 6.3 894 40.6 662 30.0
Group characteristics
Age, mean 48.4±17.29 48.7±16.41 46.1±16.27 45.2±15.75 <0.01
Gender: female, % 54.9 56.0 63.7 68.1 <0.001*
Years of school (including higher education), mean 13.3±4.16 10.7±4.82 13.3±4.39 12.3±4.52 <0.001*
Mean total use 8.8±5.50 11.1±6.30 11.9±6.45 13.3±7.39 <0.001*
Spectrum on mode of application level: at least 1 in %
n % n % n % n %
Foodstuffs 465 91.2 131 94.9 860 96.2 643 97.1 <0.001*
Intestinal absorption 358 70.2 97 70.3 775 86.7 543 82.0 <0.001*
Extras at home 48 65.5 15 74.6 107 85.3 114 87.0 <0.001*
Intranasal use 235 46.1 58 42.0 521 58.3 350 52.9 <0.001*
Inhalation 155 30.4 57 41.3 321 35.9 261 39.4 <0.01
Local oral effects 138 27.1 48 34.8 339 37.9 247 37.3 <0.001*
Topical use in throat 124 24.3 50 36.2 289 32.3 282 42.6 <0.001*
External use 334 9.4 103 10.9 763 12.0 576 17.2 <0.001*
Mean use of items per mode of application group
Foodstuffs 4.2±3.25 5.7±3.64 5.1±3.54 6.1±3.99 <0.001*
Intestinal absorption 1.4±1.30 1.5±1.47 2.1±1.59 2.1±1.74 <0.001*
Extras at home 1.5±1.55 1.9±1.71 2.3±1.80 2.5±1.85 <0.001*
Intranasal use 0.5±0.66 0.5±0.65 0.7±0.74 0.6±0.69 <0.001*
Inhalation# 0.5±0.78 0.6±0.78 0.6±0.93 0.6±1.03 0.011
Local oral effects# 0.4±0.69 0.5±0.75 0.6±0.88 0.5±0.81 <0.001*
Topical use in throat# 0.3±0.52 0.4±0.57 0.4±0.56 0.5±0.65 <0.001*
External use# 0.1±0.36 0.1±0.34 0.1±0.41 0.2±0.48 <0.001*
Mean use of pharmaceutical vs. non-pharmaceutical products
Non-pharmaceutical products 8.1±5.36 10.5±6.09 10.9±6.29 12.4±7.06 <0.001*
Pharmaceutical products 0.7±0.78 0.6±0.77 1.0±0.87 0.8±0.88 <0.001*
Ratio pharmaceuticals /non-pharmaceuticals# 1:6.7 1:10.0 1:9.1 1:10.1 <0.001*
Mean use of self-care with evidence base vs. self-care without evidence base
Without evidence base 7.9±5.3 10.4±6.1 10.7±6.3 12.2±7.0 <0.001*
With evidence base 0.9±0.9 0.7±0.9 1.3±1.0 1.0±1.0 <0.001*
Ratio pharmaceuticals /non-pharmaceuticals# 1:6.1 1:9.6 1:7.8 1:9.6 <0.001*

#Kruskal-Wallis test

*Significant after correcting for multiple testing using the Benjamini & Hochberg procedure