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. 2018 Apr 13;13(4):e0195813. doi: 10.1371/journal.pone.0195813

Table 2. Hazard ratios (HRs) for mortality from pneumonia by number of teeth lost.

Number of teeth lost (excluding third molars) n Person-years Death from pneumonia Age- and sex-adjusted Multivariable-adjusteda
HR 95% CIb HR 95% CIb
0–14 18,532 177,988 26 1.00 1.00
15–27 741 6,301 17 1.56 0.81–2.99 1.60 0.83–3.10
28 502 4,089 25 2.08 1.10–3.92 2.07 1.09–3.95
Trend p = 0.024c Trend p = 0.026c
0–9 18,098 174,089 18 1.00 1.00
10–19 739 6,528 15 2.61 1.28–5.32 2.68 1.31–5.51
> 20 938 7,762 35 2.38 1.23–4.60 2.39 1.22–4.67
Trend p = 0.012c Trend p = 0.015c
Per tooth 19,775 188,378 68 1.031 1.005–1.059 1.031 1.004–1.060
p = 0.021 p = 0.025

aAdjusted for age (as a continuous variable), sex, smoking (never, former, or current smokers), medical history of diabetes (yes or no), body mass index (< 18.5, 18.5–24.9 or > 25.0 kg/m2) and vigorous physical activity (< 30 minutes/week or > 30 minutes/week). Missing covariate values were incorporated into proportional hazard models as additional categories.

bConfidence interval.

cIncreasing trend in the risk of mortality from pneumonia with an increasing number of teeth lost was statistically tested by assigning a score of 0, 1 or 2 to either the loss of 0–14, 15–27 or 28 teeth or the loss of 0–9, 10–19, or 20–28 teeth in the proportional hazard models.