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. 2018 Apr 13;13(4):e0195873. doi: 10.1371/journal.pone.0195873

Table 4. Hospitalizations, costs and LOS of sepsis from 2006 to 2015.

Indicator / Attribute 2006–2007 N (SD) 2008–2009 N (SD) 2010–2011 N (SD) 2012–2013 N (SD) 2014–2015 N (SD) Average Annual Growth Percentagec
All hospitalizations 118,014 114,834 144,636 161,100 185,874 72,446d 64.1%
ICU hospitalizations 33,466 30,543 40,477 47,894 58,542 21,092d 83.9%
% ICU hospitalizations 28.4% 26.6% 28.0% 29.7% 31.5% 29.1% 12.0%
Hospitalizations costsa
    Total cost (US$ million) 78.2 104.4 133.1 143.5 156.1 61.5d 113.3%
    Mean cost per case (US$)b 512.6 (420.6) 658.7 (683.7) 669.6 (701.8) 648.1 (687.2) 619.2 (662.2) 624.0 23.5%
Costs for hospitalizations requiring ICUa
    Total cost (US$ million) 48.2 71.0 93.0 103.0 114.1 42.9d 159.0%
    Mean cost per case (US$)b 1,220.2 (838.3) 1,928.9 (1,457.5) 1,927.5 (1,416.9) 1,808.8 (1,325.6) 1,657.1 (1,195.6) 1,708.1 42.2%
Mean LOS
    Hospitalization (days)b 9.3 (7.5) 8.8 (7.4) 8.6 (7.3) 9.0 (7.7) 9.1 (7.6) 9.0 -2.2%
    ICU (days)b 7.8 (6.7) 8.1 (7.0) 7.8 (6.7) 8.0 (6.8) 8.2 (6.8) 8.0 5.2%

aDeflated costs (December 2015, IPCA)

b5% extremes excluded

cGrowth percentage from 2006 to 2015

dAnnual average.

SD = standard deviation