Fig 5. Untreated transgenic Fgfr3^ach/+ mice draw essentially their energy from lipids.

Basal respiratory quotient (RQ = VCO₂/VO₂) during night or day fasting and feeding periods following 10 weeks of ND (A) or HFD (C) challenge. Basal carbohydrate and lipid oxidation in WT and Fgfr3^ach/+ ND (B) or HFD (D) challenged mice. Data are represented as mean ± SD (n = 8–10 mice to each group). Data followed normal distribution. **p<0.01, ***p<0.001 versus vehicle-treated WT, ^#p<0.05, ^##p<0.01 versus vehicle-treated Fgfr3^ach/+; Student’s t test.