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. Author manuscript; available in PMC: 2019 Apr 12.
Published in final edited form as: J Med Chem. 2018 Mar 26;61(7):2680–2693. doi: 10.1021/acs.jmedchem.7b01277

Figure 7.

Figure 7

Western blot for inhibition of cellular neddylation at 48 hours by DMSO, MLN4924 (positive control, 1 μM, single dose at T = 0), 49 (20 μM, dosing at T = 0, and T = 24 hr), and 52 (20 μM, dosing at T = 0, and T = 24 hr).