Table 1. Patient demographics and treatment details.

Case	Age	Sex	Systemic condition/RT complication	NPC treatment	Duration	Laterality	EOM function	Pre-op deviation (PD)	Reason for Botox trial (after failed FP)	Dose (U)	No. of injection	Deviation 6/12 after last Botox	Diplopia after Botox	Final EOM limitation	Definitive surgery	Complication with Botox	Change in deviation	Mortality
1	48	M	HT	ChemoRT 2009	1 year	LE	−1	18	Not keen for OT	3	2	6	−	−0.5	—	—	12
2	59	M	Liver and bone metastasis	Radical RT 2005	1 year	LE	4	80	Poor systemic condition	5	1	70	+	−4	BE SR+IR to LR transposition+L MR recession 2/12/11	—	10	Passed away in 2012
3	65	M	Temporal obe necrosis, panhypopituitarism, deafness, CVA, HT	RT 1985	>15 years	BE	−3	30	Poor systemic condition	5	4	6	−	−2	—	—	24	Passed away in 2015
4	48	M	Hypothyroidism, pancytopenia, second primary—CA tongue	RT 1996	2 years	LE	−2	45	Not keen for OT Failed FP	5	4	8	−	−1	—	—	37
5	48	M	NPC with skull base and prepontine region involvement. History of DVT	RT 2007	2 years	LE	−2	45	Poor systemic condition	5	1	40	+	−4	—	—	5	Passed away in 2011
6	58	M	IHD, CVA	RT 1987	1 year	RE	−1	45	Not keen for OT	5	3	12	+	−2	—	Transient ptosis	33
7	47	M	Hypothyroidism, mild swallowing impairment	Radical RT 2002	4 years	RE	−1	18	Not keen for OT	2.5	12	10	−	−1	BE MR recession 15/6/16	Transient ptosis	8
8	51	M	Lung metastasis, hypothyroidism	Radical RT 2002	5 years	RE	−1	35	Not keen for OT	5	9	35	+	−2	BE IR/ SR transposition+MR recession 9/8/13	Transient ptosis	0	Passed away in 2015
9	54	M	Hearing impairment	Radical RT 1982	4 years	LE	−2	30	Not keen for OT	2.5	9	30	+	−2	—	—	0
10	64	M	CVA, swallowing impairment	RT 1989, 2007	1 year	RE	−2	45	Poor systemic condition	2.5	1	25	+	−1	—	—	20	Passed away in 2009
11	34	M	NPC with skull base, sinus, brain and lung metastasis	Palliative RT 2009	1 year	BE	−1	50	Poor systemic condition	5	1	45	+	−2	—	—	5	Passed away in 2012
12	61	M	Bone metastasis, Hx of BCC, R carotid stenosis	palliative RT 1999	1 year	BE	−1	35	Poor systemic condition	2.5	1	8	−	−1	—	—	27	Passed away in 2011
13	53	F	Hypothyroidism, temporal lobe necrosis	Radical RT 1990, 1993	1 year	BE	−1	20	Not keen for OT	2.5	1	20	+	−2	—	Transient vertical deviation	0
14	50	M	Lipids	RT 1991	10 years	BE	−2	45	Not keen for OT	5	3	20	+	−2	BE SR+IR transpose to LR and BE MR recession	—	25
15	53	M	Hypothyroidism, R carotid stenosis	NPC with RT 1984	2 years	BE	−2	45	Not keen for OT	5	2	45	+	−2	BE SR/IR trasnfer±R MR recession±L SR / IR transfer	—	0
16	45	M	Hypothyroidism, persistent hypokalemia and hypomagnesiumia after chemotherapy	ChemoRT 2007	2 years	LE	−1	35	Not keen for OT	5	1	25	+	−2	—	—	10
17	59	F	Hypothyroidism, DM, lipid	RT 1982, 1987 (palliative intent)	2 years	BE	−2	30	Not keen for OT	5	3	25	+	−2	BE MR recession 2/10/15	—	5
18	44	M	Depression	ChemoRT 2008	2 years	BE	−1	16	Not keen for OT	2.5	1	10	−	−1	—	—	6
19	62	M	Second primary HCC, HBV carrier	Radical RT 2009	1 year	RE	−4	80	Not keen for OT	5	1	80	+	−4	RE SR+IR to LR half tendon transfer±MR recession	—	0
20	53	M	Hypothyroidism, Dysphagia, Hx of SAH with LP shunt in 2008	RT 1985, 1992	6 months	RE	−1	20	Poor systemic condition	2.5	1	12 (EP)	−	−1	—	—	8	Passed away in 2014
21	69	F	Hearing loss	RT 1994	6 months	LE	−3	55	Not keen for OT	5	4	15	+	−1	—	Transient vertical deviation	40	Passed away in 2013
22	49	M	Panhypopituitarism, HT, CVA	Radical RT 1998	1 year	BE	3	35	Not keen for OT	5	1	30	+	−3	RE SR/IR half split tendon transfer+MR recession 6.5 mm BE	Transient ptosis	5	Passed away in 2014
23	62	M	Panhypopituitarism, anemia	RT 1982, 1994	2 years	BE	−2	45	Not keen for OT	5	5	40	+	−2	—	—	5
24	61	M	Baroreceptor failure with labile BP	ChemoRT 2009, 2012	1 year	RE	−2	35	Not keen for OT	5	1	35	+	−3	SR/IR transposition±R MR recession	Transient vertical deviation	0	Passed away in 2014
25	35	M	Temporal lobe necrosis with seizures, hypopituitarism, dysphagia	RT 1979	5 years	BE	−2	45	Poor systemic condition	5	1	45	+	−2	—	—	0