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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Brain Stimul. 2017 Nov 15;11(2):271–277. doi: 10.1016/j.brs.2017.11.007

Figure 5. Stimulation intensity and pulse width influence VNS-dependent changes in tone-evoked response strength.

Figure 5

Response strength to high frequency tones (8–16 kHz, 45–75 dB) minus the response strength to low frequency tones (1–2 kHz, 45–75 dB) in naïve and VNS treated animals. In naïve and 200μA:100μs VNS groups, A1 neurons fired more robustly in response to low frequency tones. This bias was reduced in rats who received 200μA:500μs or 800μA:100μs VNS due to a shift in response strength to favor high frequency tones.