. Author manuscript; available in PMC: 2019 May 1.

Published in final edited form as: Acta Neurochir (Wien). 2018 Jan 6;160(5):1005–1021. doi: 10.1007/s00701-017-3438-z

Table 4.

Results of Gross tumor resection rate and 95% Confidence Interval in the Following case (Combine Subgroups Using Fixed- and random-effect model)

Operative modality	Number Of studies	Fixed-effect model		Random-effect model		Heterogeneity		P-interaction		P-value for Begg’s test
Operative modality	Number Of studies	GTR rate (%)	95%-CI	GTR rate (%)	95%-CI	I² value (%)	P-heterogeneity	Fixed effect model	Random effect model	P-value for Begg’s test
ETSS PA Overall	50	74.0	72.6–75.3	71.2	66.2–75.8	92.1	<0.01	<0.01	0.44	0.33
MTSS PA Overall	19	66.6	64.6–68.6	67.5	58.5–75.4	84.8	<0.01	<0.01	0.44	0.33
ETSS FPA	13	75.8	72.8–78.5	76.7	70.5–81.8	63.9	<0.01	0.92	0.67	0.91
MTSS FPA	5	75.5	69.1–80.9	74.1	62.2–83.2	79.0	<0.01	0.92	0.67	0.91
ETSS NFPA	19	71.0	68.7–73.3	74.1	67.5–79.7	86.3	<0.01	<0.01	0.127	0.08
MTSS NFPA	8	60.7	57.3–64.0	64.6	53.1–74.7	87.4	<0.01	<0.01	0.127	0.08

Abbreviations: GTR, gross total resection, PA, pituitary adenoma; NR, not reported; FPA, functional pituitary adenoma; NFPA, nonfunctional pituitary adenoma; ETSS, Endoscopic Transsphenoidal surgery; MTSS, Microscopic Transsphenoidal Surgery