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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Acta Neurochir (Wien). 2018 Jan 6;160(5):1005–1021. doi: 10.1007/s00701-017-3438-z

Table 4.

Results of Gross tumor resection rate and 95% Confidence Interval in the Following case (Combine Subgroups Using Fixed- and random-effect model)

Operative modality Number Of studies Fixed-effect model Random-effect model Heterogeneity P-interaction P-value for Begg’s test
GTR rate (%) 95%-CI GTR rate (%) 95%-CI I2 value (%) P-heterogeneity Fixed effect model Random effect model
ETSS PA Overall 50 74.0 72.6–75.3 71.2 66.2–75.8 92.1 <0.01 <0.01 0.44 0.33
MTSS PA Overall 19 66.6 64.6–68.6 67.5 58.5–75.4 84.8 <0.01
ETSS FPA 13 75.8 72.8–78.5 76.7 70.5–81.8 63.9 <0.01 0.92 0.67 0.91
MTSS FPA 5 75.5 69.1–80.9 74.1 62.2–83.2 79.0 <0.01
ETSS NFPA 19 71.0 68.7–73.3 74.1 67.5–79.7 86.3 <0.01 <0.01 0.127 0.08
MTSS NFPA 8 60.7 57.3–64.0 64.6 53.1–74.7 87.4 <0.01

Abbreviations: GTR, gross total resection, PA, pituitary adenoma; NR, not reported; FPA, functional pituitary adenoma; NFPA, nonfunctional pituitary adenoma; ETSS, Endoscopic Transsphenoidal surgery; MTSS, Microscopic Transsphenoidal Surgery