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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Matern Fetal Neonatal Med. 2017 Oct 11;32(4):527–541. doi: 10.1080/14767058.2017.1384460

Table 3.

Pregnancy outcomes of study population

Characteristics Intra-amniotic
inflammation (−)/
MIAC (−)
(Group 1, n=55)
P* Adjusted
P*,§
Intra-amniotic
inflammation (+)/
MIAC (−)
(Group 2, n=26)
P Intra-amniotic
inflammation (+)/
MIAC (+)
(Group 3; n=9)
P Adjusted
P,§
Gestational age at delivery, weeks**,†† 34.0 (31.4–35.1) .004 - 30.2 (26.1–34.6) NS 28.4 (25.9–33.1) .003 -
Spontaneous delivery
    <24 hours 6/54 (11%) .001 .002 12/26 (46%) NS 5/9 (56%) .006 .003
    <48 hours 7/54 (13%) <.001 <.001 16/26 (62%) NS 5/9 (56%) .009 .007
    <7 days 17/53 (32%) <.001 <.001 23/26 (89%) NS 7/9 (78%) .021 .017
Spontaneous preterm delivery
    <34+0 weeks‡‡ 23/50 (46%) .003 .021 18/21 (86%) NS 7/8 (88%) NS NS
    <36+0 weeks 40/49 (81%) NS NS 25/26 (96%) NS 8/8 (100%) NS NS
Acute histologic chorioamnionitis 12/46 (26%) NS NS 11/21 (52%) NS 5/8 (63%) NS NS
Funisitis 2/47 (4%) NS NS 4/21 (19%) NS 4/8 (50%) .003 .003

Data presented as median (interquartile range) or n/N (%)

MIAC, microbial invasion of amniotic cavity; NS, not significant.

*

Comparison between groups 1 and 2.

Comparison between groups 2 and 3.b

Comparison between groups 1 and 3.

§

Adjusted for gestational age at amniocentesis and the cervical dilatation (logistic regression analysis).

**

Two women whose gestational age at delivery were not known were excluded.

††

P<.05 by Kruskal-Wallis ANOVA test.

‡‡

Cases with gestational age at amniocentesis ≥ 34+0 weeks were excluded from the analysis.