Skip to main content
. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Curr Opin Biotechnol. 2017 Oct 13;51:1–7. doi: 10.1016/j.copbio.2017.09.005

Figure 4.

Figure 4

Cartoon representation of domain-based cores (a) and of shells with selective permeability (b). (a) Top panel: a chimeric protein tagged with an EP comprised of protein domains for a metabolic reaction. Lower panel: a linear scaffold tagged with an EP that is able to form protein-protein interaction with enzymes of a metabolic pathway. (b). Top panel: introduction of a foreign or a modified shell protein to tune permeability for specific metabolites. Lower panel: engineering of catalytic sites in the pore of shell proteins that will convert metabolites to the form required by the encapsulated pathway.