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. 2018 Apr 13;9:1462. doi: 10.1038/s41467-018-03949-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — MSM-associated sublineages and antimicrobial resistance associations in context. The midpoint rooted maximum likelihood phylogenetic trees are shown for PG3 of S. flexneri 2a and Lineage III of S. sonnei. Scale bars in single nucleotide polymorphisms (SNPs) are shown below each phylogeny. Patient demography of isolates is shown overlaid on tips according to the inlaid key with circles of patients reporting recent travel to regions endemic for shigellosis being hollow. MSM-associated sublineages are labelled and coloured according to the inlaid key. Anticipated resistance phenotypes for azithromycin, ciprofloxacin (only triple QRDR mutants), and ESBL are shown in adjacent tracks