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. 2018 Apr 13;8:5969. doi: 10.1038/s41598-018-24320-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of the presence/absence of the apoE4 isoform in two cohorts of 230 (study cohort) and 50 (validation cohort) plasma samples by ELISA or by a turbidimetric assay based on LEIT. (A) Analysis of the presence of apoE4 in the study cohort of 230 plasma samples by ELISA setup stratified by APOE genotype. (B) Analysis of the presence of apoE4 in the validation cohort of 50 plasma samples by ELISA stratified by APOE genotype. (C) Analysis of the presence of apoE4 in the validation cohort of 50 samples by a turbidimetric assay stratified by APOE genotype. Error bars represent median with interquartile range.