FIG 1.

Relative infectious potential of chimeric viruses on a per-infectious-particle basis. Infectivity values for chronic and recently transmitted viruses are expressed in terms of the number of relative light units (RLU) as log₁₀ values. Particle infectivity is defined by the infectious titer determined on TZM-bl cells. (a) Particle infectivity based on the number of RLU for each individual is presented. The box plot represents the infectivity of a single viral particle of multiple variants from each infected individual. Infections were performed in TZM-bl cells with virus at an MOI of 0.005 in the presence of DEAE-dextran. Pairwise comparisons were performed using the Mann-Whitney test, and a P value of <0.05 was considered statistically significant. (b) Particle infectivity of the chronic control, recently transmitted, and TF viruses. Pairwise comparisons were performed using the Mann-Whitney test, and a P value of <0.05 was considered statistically significant.