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Proportions of isolates with Sabin 2 amino acid residues (shown inside each circle) or replacement residues (colored sectors) in the helix wheel of hypervariable positions 1001 to 1018. The numbers correspond to VP1 residue positions; the letters indicate the most frequently detected residue at each position. The numbers outside the circles are the numbers by position of each residue among the 403 cVDPV2 isolates analyzed.
