Table 1.
Proinflammatory cytokines
| WT Veh, n = 4 | WT Cis, n = 5 | IL-33 Def Veh, n = 5 | IL-33 Def Cis, n = 5 | |
|---|---|---|---|---|
| IL-1, pg/g | 74 ± 24 | 521 ± 141* | 46 ± 8 | 95 ± 30 |
| IL-2, pg/g | 72 ± 15 | 102 ± 19 | 58 ± 15 | 113 ± 36 |
| IL-4, pg/g | 48 ± 10 | 34 ± 6 | 38 ± 8 | 34 ± 18 |
| IL-5, pg/g | 0.01 ± 0.002 | 0.06 ± 0.04 | 0.01 ± 0.003 | 0.02 ± 0.003 |
| IL-6, pg/g | 728 ± 210 | 1,991 ± 318* | 562 ± 134 | 2,113 ± 295** |
| IL-10, pg/g | 87 ± 27 | 255 ± 21* | 73 ± 13 | 410 ± 67** |
| IL-12, pg/g | 918 ± 277 | 2,102 ± 254* | 899 ± 269 | 2,686 ± 390** |
| CXCL1, pg/g | 117 ± 47 | 3,797 ± 368* | 184 ± 29 | 5,954 ± 1,042** |
| TNF-α, pg/g | 55 ± 16 | 331 ± 62* | 54 ± 11 | 266 ± 21** |
| IFN-γ, pg/g | 4.2 ± 1.5 | 5.4 ± 0.09 | 3.1 ± 0.04 | 4 ± 1.3 |
WT, wild-type; Veh, vehicle; Cis, cisplatin-induced acute kidney injury; Def, deficient.
P < 0.05 vs. WT Veh;
P < 0.05 vs. IL-33 Def Veh.