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Food intake response to acute leptin administration. The change (Δ) in 24-h food intake after a saline injection subtracted from food intake response after leptin injection (5 mg/kg ip) in PTP1Bflox/flox (n = 15) and PTP1Bflox/flox/POMC-Cre (n = 11) mice. Data are expressed as means ± SE. There were no statistically significant changes as assessed by 2-way ANOVA with post hoc Sidak’s multiple comparison.
