Fig. 7.

Liver triacylglycerol content in male (n = 6) and female (n = 4) PTP1B^flox/flox and male (n = 4) and female (n = 6) PTP1B^flox/flox/POMC-Cre mice fed a HFD. A: PTP1B^flox/flox and PTP1B^flox/flox/POMC-Cre liver sections stained for Oil Red O and visualized at ×200 magnification. The nucleus was counterstained with Mayer’s hematoxylin. B: PTP1B^flox/flox and PTP1B^flox/flox/POMC-Cre liver triacylglycerol content (mg/dl). Data are expressed as means ± SE. *P < 0.05. B: unpaired Student’s t-test.