Table 1.

Summary of intervention and cross-sectional studies that have administered sustained shear stress flow-mediated dilation and, where applicable, reactive hyperemia flow-mediated dilation

	Artery	Technique	SS-FMD	RH-FMD	Reference
Intervention	Arrows versus preintervention
Prior antegrade shear stress	Brachial	Rhythmic handgrip	↑		1
l-NMMA and EDHF receptor inhibition	Radial	Hand heating	↓		5, 8
Angiotensin converting enzyme inhibitors in congestive heart failure	Radial	Hand heating	↑		45
l-NMMA and aspirin	Radial	Hand heating	↔		60
Endothelin type B receptor inhibition	Radial	Hand heating	↓		6
Anemia correction in end-stage renal disease	Brachial	Forearm heating	↑		94
Antioxidant	Brachial	Progressive handgrip	↓		72
Antioxidant or exercise training in the elderly	Brachial	Progressive handgrip	↑		20
Acute and chronic folic acid ingestion in the elderly	Brachial	Progressive handgrip	↑		73
l-NMMA	Brachial	Progressive handgrip	↓		100
l-NMMA in the elderly	Brachial	Progressive handgrip	↓		93
Ascorbic acid and l-NMMA in the elderly	Brachial	Progressive handgrip	↔		92
High-fat meal	Brachial	Rhythmic handgrip	↔	↓	62
Altered contraction duty cycles	Brachial	Rhythmic handgrip	↔		49
Cold pressor test	Brachial	Rhythmic handgrip	↔		83
Acute mental stress	Brachial	Rhythmic handgrip	↔	↓	84
Acute mental stress and cold pressor test	Brachial	Rhythmic handgrip	↑		85
Cross-sectional	Arrows versus healthy controls
Uncomplicated type I diabetes	Radial	Hand heating	↓	↔	3
Hypertension	Radial	Hand heating	↓	↓	7
Autosomal dominant polycystic kidney disease	Radial	Hand heating	↓	↔	56
End-stage renal disease	Brachial	Forearm heating	↓		94
Hypercholesterolemia	Brachial	Distal acetylcholine infusion	↔	↓	60
Young smokers	Brachial	Rhythmic handgrip	↓	↔	25
Obese young adults	Brachial	Rhythmic handgrip	↓	↔	81
Systemic sclerosis	Brachial	Progressive handgrip	↓		57

SS-FMD, sustained shear stress flow-mediated dilation; RH-FMD, reactive hyperemia flow-mediated dilation; l-NMMA, N^G-monomethyl-l-arginine.