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. 2018 Apr 13;37:82. doi: 10.1186/s13046-018-0753-z

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Quantitative proteomic analysis between Ctrl-SW480 and shDDHD1-SW480 cells. a Volcano plot of 1469 quantified proteins illustrating expression increases and decreases following DDHD1 silencing. Red dots correspond to proteins showing a fold change (FC) ≥ ±1.5 in relative abundance and a p-value < 0.05 (values indicated by vertical and horizontal dashed lines) and considered significantly differentially modulated in Ctrl-SW480 and shDDHD1-SW480 cells. b Diagram on the left illustrates the number of proteins quantified by SWATH-MS that resulted unchanged or significantly changed (Fold Change ≥ ±1.5; p < 0.05). Diagram on the right indicates the number of proteins up- and down-modulated by DDHD1-silencing. Numbers in parentheses indicate the percentage of total proteins