Cell-killing curve of LMB-12, LMB-164, LMB-20, LMB-182, LMB-170, and LMB-172 on KLM1, A431/H9, and L-55. Representative cytotoxicity assay on mesothelin-positive cancer cell lines using WST8 assay after 3 d incubation with RIT. KLM1, pancreatic cancer cell line; A431/H9, epidermoid carcinoma cell line transfected with MSLN cDNA; L-55, lung carcinoma.