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. 2018 Mar 26;115(15):E3501–E3508. doi: 10.1073/pnas.1721780115

Table 2.

Summary of mouse serum half-life and albumin-binding properties of ABD–immunotoxin fusion proteins

LMB no. Half-life, min SE AUC SE MSA half-maximum binding, nM HSA half-maximum binding, nM
LMB-12 12.7 0.8 255.2 38.0 None None
LMB-164 193.8 60.2 11,255.0 2,434.0 0.10 0.08
LMB-20 7.9 0.7 248.0 22.0 None None
LMB-182 142.0 16.3 8,073.5 1,338.3 0.11 0.09
LMB-170 101.3 22.9 7,609.3 647.0 2.15 0.12
LMB-172 144.1 20.8 9,017.8 1,100.6 0.40 0.09