Table 3.
Associations of Characteristics Shared by RA and Control Groups with Abnormal Urinary Albumin to Creatinine Ratio
| Adjusted* | |||||
|---|---|---|---|---|---|
|
| |||||
| RA | Control | ||||
| OR | p | OR | p | p-interaction | |
| Age, per year | 1.03 | 0.21 | 1.05 | 0.031 | 0.54 |
| Any college vs. none | 0.50 | 0.11 | 0.44 | 0.034 | 0.81 |
| Hormone replacement | 0.65 | 0.60 | 0.45 | 0.10 | 0.70 |
| Serum creatinine, per mg/dL | 0.63 | 0.64 | 4.50 | 0.088 | 0.013 |
| Diabetes | 1.05 | 0.95 | 3.13 | 0.026 | 0.29 |
| log HOMA-IR, per log unit | 1.21 | 0.48 | 2.36 | 0.006 | 0.10 |
| Hypertension | 1.34 | 0.45 | 3.06 | 0.004 | 0.013 |
| log IL-6, per log unit | 1.90 | 0.007 | 1.24 | 0.42 | 0.23 |
| log Homocysteine | 0.32 | 0.14 | 3.14 | 0.057 | 0.017 |
| Any ARB use | 0.72 | 0.60 | 1.52 | 0.52 | 0.39 |
| Any diuretic use | 1.23 | 0.67 | 1.65 | 0.29 | 0.66 |
| Any NSAID use | 1.85 | 0.16 | 1.19 | 0.67 | 0.46 |
*
Adjusted for age, education, hormone replacement use, HOMA-IR, presence of hypertension, and IL-6 level (as appropriate)
RA=Rheumatoid Arthritis; HOMA-IR=Homeostatic Model Assessment Insulin Resistance Index; ARB=angiotensin receptor blocker; NSAID=non-steroidal anti-inflammatory drug