Table 2.

Summary of Functional Parameters obtained from Baseline and Occlusion PV loops separated by gender at 3 months of age (Figure 4). Rate of pressure change maximum and minimum (dP_max and dP_min), end systolic volume (ESV), end diastolic volume (EDV), end systolic pressure volume relationship (ESPVR), end diastolic pressure volume relationship (EDPVR).

	Non-Tg (male)	D230N-Tm (male)	Non-Tg (female)	D230N-Tm (female)
dPmax (mmHg/sec)	9256.3 ± 806.9	6894.4 ± 501.2*	9273.7 ± 979.7	5900.4 ± 515.4#
dPmin (mmHg/sec)	−8830.74 ± 756.5	−8919.5 ± 681.4	−7806.0 ± 210.7	−7241.0 ± 876.4
ESV (uL)	27.1 ± 4.3	55.4 ± 7.3*	13.37 ± 3.3	45.1 ± 6.4#
EDV (uL)	65.8 ± 6.3	102.9 ± 12.2*	42.0 ± 7.9	78.7 ± 8.0#
ESPVR	3.8 ± 0.3	2.1 ± 0.3*	4.6 ± 0.03	1.9 ± 0.1####
EDPVR	0.03 ± 0.004	0.03 ± 0.01	0.04 ± 0.004	0.05 ± 0.01

Values are reported mean ± S.E.M. student’s t test was used to assess significance vs Non-Tg.

^*p < 0.05, compared to Non-Tg males,

^#p < 0.05,

^####p < 0.0001 compared to Non-Tg females. N = 3–4.