Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of Calorimetric Data obtained from DSC and melt temperature from CD (Figure 7) of WT-Tm and D230N-Tm.
| DSC | CD | ||||
|---|---|---|---|---|---|
| Domain-1 (C-terminus) | Domain-2 (N-terminus) | (Total Tm) | |||
| Tm°C | ΔHkJ/mol (% total) | Tm°C | ΔHkJ/mol (% total) | Tm°C | |
| α-Tm-WT | 43.7 ± 0.06 | 604 ± 19 (56%) | 53.1 ± 0.1 | 381 ± 9 (44%) | 44.2 ± 0.1 |
| α-Tm-D230N | 44.7 ± 0.06**** | 693 ± 8 (69%) | 52.8 ± 0.1** | 448 ± 21 (31%) | 45.4 ± 0.1**** |
Values are reported as mean ± S.E.M.
p < 0.01
p < 0.0001 compared to WT-Tm.
