Table 4.
A comparison of the quantitative DESS-EXP morphometry and T2 relaxometry measurements and the semi-quantitative MOAKS measurements for patients with osteoarthritis of Kellgren-Lawrence grades (KLG) of 0, 2, and 3. Entries in bold represent a significant difference as compared to the KLG0 cohort.
| KL Grade | Quantitative Parameters | ||
|---|---|---|---|
| 0 | 2 | 3 | |
| Cartilage Thickness (mm) | 2.09 ± 0.24 | 1.83 ± 0.23 (p = 0.31) | 1.74 ± 0.32 (p = 0.69) |
| Meniscus Volume (mm3) | 562 ± 105 | 842 ± 405 (p = 0.31) | 642 ± 279 (p = 0.69) |
| Cartilage T2 (ms) | 33.8 ± 2.7 | 41.8 ± 5.7 (p = 0.02) | 46.5 ± 6.4 (p < 0.01) |
| Meniscus T2 (ms) | 12.7 ± 1.0 | 16.6 ± 3.1 (p = 0.02) | 16.8 ± 4.0 (p < 0.01) |
|
| |||
| KL Grade | Semi-Quantitative MOAKS Parameters | ||
| 0 | 2 | 3 | |
|
| |||
| Cartilage Thickness | 0 ± 0 | 1.5 ± 1.7 (p = 0.17) | 5.2 ± 3.9 (p = 0.04) |
| Cartilage SA | 0.2 ± 0.4 | 2.4 ± 1.5 (p = 0.04) | 6.8 ± 4.1 (p = 0.04) |
| Osteophytes | 0 ± 0 | 11.8 ± 15.4 (p = 0.01) | 20.1 ± 7.6 (p = 0.01) |
| Meniscus Tears | 0 ± 0 | 0 ± 0 (p = 1.00) | 0.3 ± 0.7 (p = 1.00) |
| Meniscus Signal | 0.3 ± 0.7 | 1.2 ± 2.2 (p = 0.72) | 1.0 ± 1.3 (p = 0.40) |
| Meniscus Extrusion | 0 ± 0 | 0.5 ± 0.5 (p = 0.17) | 0.9 ± 0.9 (p = 0.17) |
| BML Subregions | 1.2 ± 0.8 | 2.4 ± 1.5 (p = 0.20) | 8.3 ± 3.8 (p = 0.01) |
| BML Sizes | 2.0 ± 2.2 | 1.7 ± 0.8 (p = 0.79) | 4.7 ± 2.0 (p = 0.07) |
| Hoffa Synovitis | 0.3 ± 0.4 | 0.1 ± 0.2 (p = 0.72) | 0.5 ± 0.7 (p = 0.84) |
| Effusion Synovitis | 0.8 ± 1.3 | 0 ± 0 (p = 0.44) | 2.1 ± 1.0 (p = 0.14) |
| Bursa | 0 ± 0 | 0 ± 0 (p = 1.00) | 0.2 ± 0.4 (p = 1.00) |
| Cysts | 0.4 ± 0.4 | 1.5 ± 0.5 (p = 0.02) | 3.6± 1.7 (p = 0.02) |
| Ligaments | 0.1 ± 0.2 | 0 ± 0 (p = 1.00) | 0.2 ± 0.4 (p = 1.00) |
| Other | 0 ± 0 | 0 ± 0 (p = 1.00) | 0.3 ± 0.3 (p = 0.17) |
|
| |||
| Total | 5.0 ± 4.8 | 17.3 ± 8.9 (p = 0.03) | 55.0 ± 20.7 (p < 0.01) |