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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Cancer Res. 2018 Jan 30;78(8):2127–2139. doi: 10.1158/0008-5472.CAN-17-2649

Figure 3.

Figure 3

CT and AT schedules applied to tumors with a variety of phenotypes. Tumor phenotypes were initialized by normal distributions with mean sensitivity s and standard deviation σs: A) s=100% and σs=5%, B) s=100% and σs=25%, C) s=60% and σs=5%, and D) s=60% and σs=25%. Top panels show the dose schedules for each treatment strategy, middle panels, the population dynamics, and lower panels, the spatial configurations at several time points.