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. 2017 Dec 12;10(2):571–581. doi: 10.1007/s12551-017-0368-1

Table 1.

Timeline of the studies of cytoskeletal motors

1941, 1942 Discovery of myosin and actomyosin (Banga and Szent-Györgyi 1941–1942)
1943 Discovery of G- and F-actin (Straub 1943)
1954 Proposal of the sliding filament theory of muscle contraction (Huxley and Niedergerke 1954; Huxley and Hanson 1954)
1965 Discovery of the first microtubule motor, dynein (Gibbons and Rowe 1965)
1967 Discovery of tubulin (Borisy and Taylor 1967)
1985 Discovery of the kinesin microtubule motor (Brady 1985; Vale et al. 1985)
1989 Single-molecule assay for kinesin (Howard et al. 1989)
1993 Structures of myosin and actomyosin (Rayment et al. 1993a, b)
1994 Single-molecule assay for myosin (Finer et al. 1994)
1995 Structures of the kinesin microtubule complexes (Hirose et al. 1995; Hoenger et al. 1995; Kikkawa et al. 1995)
1996 Crystal structure of the kinesin motor (Kull et al. 1996)
1998 Visualisation of the power stroke of myosin (Dominguez et al. 1998)
1999 Single-molecule study of dynein (Sakakibara et al. 1999)
1999 Visualisation of the power stroke of kinesin (Rice et al. 1999)
2003 Visualisation of the power stroke of dynein (Burgess et al. 2003)
2011, 2012 Crystal structures of the dynein motors (Carter et al. 2011; Kon et al. 2012)