1941, 1942 |
Discovery of myosin and actomyosin (Banga and Szent-Györgyi 1941–1942) |
1943 |
Discovery of G- and F-actin (Straub 1943) |
1954 |
Proposal of the sliding filament theory of muscle contraction (Huxley and Niedergerke 1954; Huxley and Hanson 1954) |
1965 |
Discovery of the first microtubule motor, dynein (Gibbons and Rowe 1965) |
1967 |
Discovery of tubulin (Borisy and Taylor 1967) |
1985 |
Discovery of the kinesin microtubule motor (Brady 1985; Vale et al. 1985) |
1989 |
Single-molecule assay for kinesin (Howard et al. 1989) |
1993 |
Structures of myosin and actomyosin (Rayment et al. 1993a, b) |
1994 |
Single-molecule assay for myosin (Finer et al. 1994) |
1995 |
Structures of the kinesin microtubule complexes (Hirose et al. 1995; Hoenger et al. 1995; Kikkawa et al. 1995) |
1996 |
Crystal structure of the kinesin motor (Kull et al. 1996) |
1998 |
Visualisation of the power stroke of myosin (Dominguez et al. 1998) |
1999 |
Single-molecule study of dynein (Sakakibara et al. 1999) |
1999 |
Visualisation of the power stroke of kinesin (Rice et al. 1999) |
2003 |
Visualisation of the power stroke of dynein (Burgess et al. 2003) |
2011, 2012 |
Crystal structures of the dynein motors (Carter et al. 2011; Kon et al. 2012) |