Table 4. Effect of ethanol extract of Artocarpus heterophyllus stem bark on serum ALT, AST, ALP and other biochemical parameters of alloxan-induced diabetic rats .
Groups | ALT (u/l) | AST (u/l) | ALP (u/l) | Albumin (g/l) | Bilirubin(mg/dl) | Creatinine(mg/dl) | Urea (mg/dl) |
NC | 72.02±1.20* | 84.10±0.06* | 143.02±1.20* | 20.23±1.20* | 4.20±0.12* | 2.64±0.42** | 34.20±1.10* |
NDC | 126.20±0.90**** | 140.11±1.30**** | 500.11±1.02***** | 10.10±1.12***** | 15.40±0.10**** | 6.20±1.01*** | 86.19±0.18***** |
D+glib | 84.20±1.20*** | 96.10±0.06*** | 320.14±0.11**** | 13.79±0.60**** | 8.20±1.30*** | 3.20±0.10** | 56.24±1.12**** |
D+SBAH 50 | 83.94±1.42*** | 95.01±2.01*** | 284.01±0.42*** | 16.21±0.27*** | 6.38±0.12*** | 2.90±0.08* | 50.12±1.10*** |
D+SBAH100 | 76.20±1.02** | 88.10±1.10** | 246.15±0.12** | 18.53±0.80** | 5.80±0.19** | 2.70±0.06* | 41.12±0.18** |
D+SBAH150 | 73.40±0.41* | 85.25±0.20* | 153.21±2.12* | 20.10±0.31* | 4.64±0.18* | 2.66±0.10* | 34.69±1.14* |
Each value is a mean of six replicates ± SEM. Values with different superscript across the column are significantly different at p<0.05. NDC (non-diabetic control), DC (Diabetic control), D+glib (D+glibenclamide), D+ SBAH 50 (Diabetic rats received 50 mg/kg body weight of Artocarpus heterophyllus stem bark), D + SBAH 100 (Diabetic rats received 100 mg/kg body weight of Artocarpus heterophyllus stem bark, and SBAH 150 (Diabetic rats received 150 mg/kg body weight of Artocarpus heterophyllus stem bark