Table II.
Decrease of volume in patients with AD compared to controls (corrected for age)
| Region | Side | CE | Coordinates (mm) | T 38 | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Lateral subst. innominata (Ch4al) | R | 566 | 23 | 4 | −7 | 5.21 |
| Anteromedial subst. innominata (Ch2/3) | R | 8 | 6 | −5 | 3.92 | |
| Putamen | R | 24 | 6 | 0 | 3.67 | |
| Posterior subst. innominata (Ch4p) | R | 4 | 24 | −11 | −8 | 2.54 |
| Globus pallidus | R | 3 | 8 | −4 | −1 | 2.49 |
| Lateral subst. innominata (Ch4al) | L | 33 | −23 | 1 | −8 | 3.16 |
The height threshold was set at P < 0.01, uncorrected for multiple comparisons. The cluster extension, representing the number of contiguous voxels passing the height threshold was set at ≥5.
Coordinates in bold delineate a cluster and the peak T‐value (38 degrees of freedom) within the cluster. Subsequent nonbold coordinates identify further peaks within the same cluster that meet the significance level.
Brain regions are indicated by Talairach and Tournoux coordinates, x, y, and z [Talairach and Tournoux,1988]: x, the medial to lateral distance relative to midline (positive = right hemisphere); y, the anterior to posterior distance relative to the anterior commissure (positive = anterior); z, superior to inferior distance relative to the anterior commissure‐posterior commissure line (positive = superior). R/L, right/left; CE, cluster extension, number of contiguous voxels passing the height threshold.