Table 1.
Case history and MRI sequences
Cases | Age (years) | Gender | Cause of death | Previous neurological diseases | 3.0 T MRI scan | PMIa | Fixation | Plane of section | No. of studied sections | Thickness of the sections (μm) |
---|---|---|---|---|---|---|---|---|---|---|
Case 1 | 56 | Man | Myocardial infarct | None | Yes, in cranio | 15h30′ | Formalin 20%, immersion, 4 months | Frontal | 101 | 400 |
Case 2 | 66 | Woman | Blunt traumab | None | Yes, in cranio | 13h05′ | Formalin 20% immersion, 4 months | Axial | 279 | 430 |
Case 3 | 56 | Man | Myocardial infarct | None | Yes, in cranio | 14h40′ | Formalin 20% immersion, 4 months | Frontal | 285 | 560 |
MRI sequences: T1: TR = 6.3 ms, TE = 2.9 ms, TI = 791 ms, 240 9 × 240, 1 9 × 1 9 × 1 mm voxels 3D; Axial FLAIR: TR = 8613 ms, TI = 2800 ms, TE = 130 ms, 0.65 mm 9 × 0.87 mm, 1 NEX 3 mm/0.3 mm, FOV 230 mm 9 × 183 mm, 2D, DTI: b = 3000, TE = 65 ms, TR 23.650 ms, FOV 256 mm 9 × 256 mm, resolution 2.0 mm 9 × 2.0 mm 9 × 2.0 mm, NEX 2, gradient 32 directions, SENSE = 2 (AP), Flip angle = 90
PMI post-mortem interval (time between death and autopsy)
Without brain injuries