Table 2.

Results of measurements of dice similarity coefficient (DSC) and normalized weighted spectral distance (nWSD) for Case 1 (manual registration) and Case 2 (automated registration)

	N	Mean DSC ± CI 95%	SD	Min	Max	Mean nWSD ± CI 95%	SD	Min	Max
Case 1
2D warp	103	0.9642 ± 0.0186	0.0955	0.0110	0.9878	0.0066 ± 0.0005	0.0024	0.001	0.01
3D warp	1	0.9486	–	–	–	0.0045	–	–	–
Case 2
2D warp	262	0.9427 ± 0.0030	0.0291	0.7881	0.9780	0.0080 ± 0.00003	0.0002	0.008	0.009
3D warp	1	0.9675	–	–	–	0.0054	–	–	–

Mean values with 95% confidence intervals (CI 95%), standard deviations (SD), and minimal and maximal values are also listed. N is the number of pairs of slices (2D) or pairs of volumes (3D) evaluated. t test demonstrated p < 0.05 for comparison between DSC and nWSD values for 2D warps of Cases 1 and 2