Table 2.
NO APOE‐ε4a | APOE‐ε4b | ||||||
---|---|---|---|---|---|---|---|
SNV | BETA | SE | P | BETA | SE | P | GENE |
1‐207680070‐C‐T | 0.13 | 0.21 | 5.2E‐01 | 0.15 | 0.21 | 4.6E‐01 | CR1 |
1‐207741237‐C‐T | 1.61 | 0.99 | 1.0E‐01 | 1.60 | 0.96 | 9.6E‐02 | CR1 |
7‐29035428‐C‐T | 0.82 | 0.44 | 6.3E‐02 | 0.80 | 0.43 | 6.2E‐02 | CPVL |
7‐30876316‐C‐T | −0.58 | 0.42 | 1.7E‐01 | −0.50 | 0.41 | 2.3E‐01 | FAM188B |
7‐31682771‐C‐T | 0.87 | 1.25 | 4.9E‐01 | 0.86 | 1.26 | 4.9E‐01 | CCDC129 |
7‐91630531‐C‐T | 1.75 | 0.86 | 4.1E‐02 | 1.84 | 0.88 | 3.8E‐02 | AKAP9 |
7‐91667736‐A‐G | 0.35 | 0.35 | 3.2E‐01 | 0.35 | 0.38 | 3.5E‐01 | AKAP9 |
7‐143091417‐C‐T | 0.18 | 0.68 | 8.0E‐01 | 0.19 | 0.67 | 7.7E‐01 | EPHA1 |
11‐60703423‐G‐A | 0.06 | 0.45 | 8.9E‐01 | 0.00 | 0.43 | 1.0E+00 | TMEM132A |
11‐61015721‐G‐A | 0.93 | 0.54 | 8.5E‐02 | 0.81 | 0.54 | 1.3E‐01 | PGA5 |
11‐61120560‐G‐A | ‐0.08 | 0.58 | 8.9E‐01 | ‐0.07 | 0.57 | 9.0E‐01 | CYB561A3 |
11‐61250246‐G‐A | 0.10 | 0.50 | 8.4E‐01 | ‐0.02 | 0.47 | 9.6E‐01 | PPP1R32 |
11‐61546888‐G‐A | ‐0.55 | 0.26 | 3.8E‐02 | ‐0.49 | 0.26 | 5.9E‐02 | MYRF |
11‐62286666‐C‐T | 0.72 | 0.73 | 3.2E‐01 | 0.75 | 0.75 | 3.2E‐01 | AHNAK |
11‐62343562‐G‐C | 1.09 | 0.50 | 2.8E‐02 | 0.96 | 0.51 | 5.9E‐02 | ASRGL1 |
11‐62344743‐C‐T | 0.72 | 0.73 | 3.2E‐01 | 0.75 | 0.75 | 3.2E‐01 | MIR3654 |
11‐62400108‐G‐A | ‐0.31 | 0.36 | 4.0E‐01 | ‐0.26 | 0.36 | 4.7E‐01 | GANAB |
11‐62886345‐G‐A | 0.21 | 0.54 | 6.9E‐01 | 0.24 | 0.54 | 6.6E‐01 | SLC3A2 |
14‐93142861‐T‐C | 0.29 | 0.42 | 5.0E‐01 | 0.31 | 0.42 | 4.6E‐01 | RIN3 |
19‐1057919‐C‐T | 0.62 | 0.70 | 3.8E‐01 | 0.58 | 0.67 | 3.9E‐01 | ABCA7 |
Model‐ LOAD ~ Gene + Age + Sex + proportion of African ancestry + proportion of Native American Ancestry + First ten principal components.
Model‐ LOAD ~ Gene + Age + Sex + number of APOE ε4 alleles + proportion of African ancestry + proportion of Native American Ancestry + First ten principal components. (nominally significant variants are highlighted in bold).