Table 3.
Characteristics of EoE Patients with and without Fibrosis Detected
EoE with Fibrosis Detected N = 33 |
EoE with No Fibrosis Detected N = 4 |
P value | |
---|---|---|---|
Mean age in years (range) | 9.3 (1.6 – 17.8) | 5.9 (1.6 – 9.7) | 0.24 |
Males | 26 (79%) | 0 | <0.01 |
White | 17 (52%) | 4 (100%) | 0.12 |
Atopy‡ | 29 (88%) | 4 (100%) | 1.00 |
Peak eosinophil count (eos/HPF), mean ± SD | 70.2 ± 34.0 | 35.3 ± 30.1 | 0.03 |
Symptom duration in years, mean ± SD | 2.7 ± 2.3 | 0.9 ± 0.8 | 0.07 |
On therapy§ | 21 (64%) | 1 (25%) | 0.28 |
Total number of biopsies | 251 | 22 | |
Number of biopsies per patient, mean ± SD | 7.6 ± 2.3 | 5.5 ± 1 | 0.05 |
Biopsies with adequate lamina propria | 123 (49%) | 10 (45%) | 0.75 |
Patients with asthma, eczema, food allergy, or drug allergy were classified as atopy.
On PPI, topical steroid, systemic steroid, and/or dietary therapy.