Figure 1.
Patients progressing from each stage of amyotrophic lateral sclerosis with riluzole or placebo
(A) Treatment with 100 mg riluzole per day significantly prolonged time in stage 4 compared with placebo (p=0·037). (B) Treatment with all doses did not prolong time in stage 2 compared with placebo (p=0·827). (C) Treatment with all doses did not prolong time in stage 3 compared with placebo (p=0·882). HR=hazard ratio.