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. 2018 Apr 15;596(8):1433–1466. doi: 10.1113/JP275719

Figure 8. Ca2+ transients in USMCs rely on functional SR stores.

Figure 8

Aa and b, representative ST maps showing the effect of 10 μm thapsigargin on Ca2+ transient firing in USMCs. Ba–d, summary data showing the effect of 10 μm thapsigargin on USMC Ca2+ transient frequency (a), amplitude (b), duration (c) and spatial spread (d) (c = 4, n = 3). Ca and b, representative ST maps showing the effect of 10 μm CPA on Ca2+ transient firing in USMCs. Da–d, summary data showing the effect of 10 μm CPA on USMC Ca2+ transient frequency (a), amplitude (b), duration (c) and spatial spread (d) (c = 13, n = 5). E, relative expression of IP3R genes in FACS sorted and unsorted urethral cells from SMC‐eGFP mice determined by qPCR analysis, normalized to Gapdh expression (n = 4). F, relative expression of RyR genes in FACS sorted and unsorted urethral cells from SMC‐eGFP mice determined by qPCR analysis, normalized to Gapdh expression (n = 4). * p < 0.05, ** p < 0.01, **** p < 0.0001.