Table 1.
Percentage of patients in which immunoglobulin E (IgE) autoantibodies have been detected in various diseases.
| Disease | IgE against | Prevalence | Reference |
|---|---|---|---|
| Allergic rhinoconjunctivitis | Profilin | (16) | |
| Asthma | n.a. | n.a. | (17, 18) |
| Atopic dermatitis | >140 IgE-binding self-antigens | 23–91% | (19, 20) |
| Autoimmune pancreatitis | n.a. | n.a. | (21) |
| Bullous pemphigoid | BP 180 or 230 | 22–100% | (22) |
| Chronic spontaneous urticaria | Thyroidperoxidase (TPO), double stranded DNA (dsDNA), IL-24 | 0–80% | (23) |
| Graves disease | TPO, muscle autoantigens | 67% | (24, 25) |
| Multiple sclerosis (MS) | Small myelin protein-derived peptides | n.a. | (26) |
| Pemphigus | Desmoglein1, Desmoglein 3, Lamininin-332 und LJM11 | 11–81% | (22) |
| Rheumatoid arthritis | ANA, anti-citrullinated protein? | 60% | (27) |
| Systemic lupus erythematodes and lupus nephritis | dsDNA, Sm, SS-A/Ro, SS-B/La, APEX, MPG, CLIP4, ANA, RNP, nucleosome, specific IgE, acidic ribosomal P2 protein | 3.6–82% | (28) |
| Uveitis | Retinal S antigen | 69% | (29) |
n.a., not assessed.