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Flow diagram of the experimental design employed in the conventional rats. (A) Rats received DMSO (controls) or oxindole or isatin at 2 different doses (treated) through an intra-peritoneal (i.p.) injection. (B) Rats received corn oil (controls) or indole (treated) through an intra-cecal (i.c.) injection. Eye blinking frequency and locomotor activity were measured in (A) and (B) animals.
